Photoswitched DNA-binding of a photochromic spiropyran.
نویسندگان
چکیده
The dramatically different DNA-binding properties of the two isomeric forms of a photochromic spiropyran have been demonstrated, enabling photoswitched DNA binding. The closed, UV-absorbing form shows no signs of interaction with DNA. Upon UV exposure the spiropyran is isomerized to the open form that binds to DNA by intercalation. The process is fully reversible as the corresponding dissociation process is induced by visible light.
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 130 36 شماره
صفحات -
تاریخ انتشار 2008